Issue

After installing Windows Updates on a Windows Server 2008R2 server, Veritas Backup Exec Administrative Console crashes on launch with the following error.

BackupExec has stopped working
Details:
Problem signature:
  Problem Event Name:    CLR20r3
  Problem Signature 01:    BackupExec.exe
  Problem Signature 02:    20.0.1188.1650
  Problem Signature 03:    5b5b3903
  Problem Signature 04:    mscorlib
  Problem Signature 05:    4.8.4110.0
  Problem Signature 06:    5de6dafa
  Problem Signature 07:    113a
  Problem Signature 08:    61
  Problem Signature 09:    System.Reflection.AmbiguousMatch
  OS Version:    6.1.7601.2.1.0.272.7
  Locale ID:    2057
  Additional Information 1:    a10f
  Additional Information 2:    a10f1727f0cb04d1a53f76cc240325be
  Additional Information 3:    990c
  Additional Information 4:    990c6bf0f28663f36ab65b91a91027fd

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Resolution

The issue was caused by the .NET Framework 4.8 upgrade installed by the Windows Update. It was resolved by uninstalling .NET Framework 4.8 and reinstalling .NET Framework 4.5.2 from the Backup Exec installation media (BE\WinNT\Install\DotNetFx\NDP452-KB2901907-x86-x64-AllOS-ENU.exe).

Windows Server 2008R2
Backup Exec V-Ray Edition 20.2